Advanced Fibre Communications
Petaluma, CA

Invested: January 1993
Merged with Tellabs
Nasdaq: TLAB


Advanced Fiber Communications is a next-generation digital loop carrier. The company's products provide affordable advanced telecom capabilities to phone companies with low- to medium-density subscriber concentrations. The products are sold directly to telephone companies and are cost-effective for the smaller markets servicing fewer than 2,000 subscribers.

www.tellabs.com
 

Aldus
San Jose, CA
Invested: January 1984
Acquired by Adobe
Nasdaq: ADBE

Aldus is a pioneer for desktop publishing for personal computers. The Company's software allows users to design, edit and lay out high-quality printed communications such as newsletters, brochures, manuals and other more complex technical documents, on a personal computer and send output to a printer or typesetter. Its market is low-end desktop publishing.

www.adobe.com
 

Artificial Muscle, Inc.
Menlo Park, CA
Invested: February 2004

Artificial Muscle, Inc. (AMI) is an early stage smart materials company that will design and manufacture new solid-state actuator components for use in speakers, generators, motors, pumps, valves and solenoids using a fundamentally new, patented, electro-active polymer (EAP) technology that will allow engineers to design smaller, lighter, cheaper, and more efficient products.

www.artificialmuscle.com
 

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Artemis Medical
Hayward, CA

Invested: July 1999
Acquired by Johnson & Johnson
NYSE: JNJ


Artemis Medical designs and develops innovative medical devices to improve earlier diagnosis and treatment of cancer. Its technologies provide physicians minimally-invasive alternatives to open surgical techniques used in cancer surgery today. These products will serve the needs of patients, physicians, and healthcare payers.

www.artemismedical.com
 

Asthmatx
Mountain View, CA

Invested: December 2005


Asthmatx has developed and patented a radiofrequency catheter and controller for reducing the amount of airway smooth muscle tissue in the lungs of asthma patients. This procedure improves the pulmonary function of moderate and severe asthmatics. Over 13 million adults in the U.S. suffer from asthma, roughly 10% or 1.3 million have been diagnosed with severe asthma.

www.asthmatx.com
 

BioSeek
Burlingame, CA
Invested: January 2002

Bioseek is a provider of postgenomic target validation and drug development. The company addresses the need for more efficient and predictive drug discovery technologies and is focused on applying its proprietary technologies to the identification, validation, and commercialization of therapeutic targets and pharmaceuticals.  Bioseek's initial customers/partners will be biotechnology and pharmaceutical companies.

www.bioseekinc.com
 

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Capella
San Jose, CA
Invested: June 2001

Capella delivers intelligent subsystems for managing traffic through the intersections of next-generation optical networks. As the traffic in optical networks evolves toward IP dominated content driven by the explosion of broadband services, the ability to route, monitor, protect, and maintain optical wavelengths dynamically, remotely, and reliably is essential. Only Capella's WavePath® Wavelength Selective Switch (WSS) with integrated optical channel monitoring (OCM) provides this comprehensive functionality enabling carriers the flexibility and scalability to easily grow their networks while reducing capital and operational expenses associated with planning, deployment, provisioning, and maintenance.


www.capellainc.com
 

CardioGenesis
Foothill Ranch, CA
Invested: November 1993
Acquired by Eclipse Surgical
Nasdaq: CGCP.OB

CardioGenesis is the leader in transmycardioal revascularization. This novel minimally-invasive laser based technology offers an option for patients who are not candidates for open heart bypass surgery or percutaneous transluminal coronary angioplasty (PTCA) as it does not rely on re-establishing blood flow through the coronary arteries by conventional means such as coronary artery bypass surgery CABG) or PTCA. There are approximately 30,000 patients who could be candidates for TMR.


www.cardiogenesis.com
 

Casabi
Menlo Park, CA

Invested: August 2005


Casabi is creating an innovative communications service that turns traditional home phones into "smart-phones" that are Internet-connected. The new features will be numerous and include integration with phone directory, peer-to-peer VOIP calling, instant messaging presence, local search, and ring-tone and screen customization. Distribution partnerships are in development with Internet Portals and RBOCs.

www.casabi.com
 

Ciena
Linthicum, MD
Invested: April 1994
Nasdaq: CIEN

Ciena is a pioneer in optical dense wavelength division multiplexing (DWDM) technology used in fiber optic systems. The Company produces products that alleviate bandwidth constraints in high traffic fiberoptic routes which eliminates the need for new fiber installations. Target customers include interexchange carriers, regional Bell Operating Companies, regional fiber optic carriers such as and international public telephone & telegraph companies.

www.ciena.com
 

Cobalt Networks
Mountain View, CA
Invested: September 1997
Acquired by Sun Microsystems
Nasdaq: SUNW

Cobalt is a pioneer in service appliance technology. The company’s primary focus is on Linux-based appliances that master a single function such as Web hosing or managing. The target markets include small and midsized businesses, departmental intranets, educational organizations, ISPs, web developers, and remote offices.

www.cobalt.com
 

Cooking.com
Santa Monica, CA
Invested: March 1999

Cooking.com is the leading online retailer of best-of-brand cooking-related products and specialty foods. The site offers around-the-clock accessibility to one of the broadest product selections of top brand, cooking-related items on the Web. Additionally, Cooking.com provides thousands of recipes, cooks' tips and technique videos, Community Kitchen (an online forum), and feature articles and menus from renowned chefs, cookbook authors and restaurateurs, creating a unique destination for people who love to cook and enjoy gourmet food.


www.cooking.com
 

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CryoGen
San Diego, CA
Invested: October 1995
Acquired by American Medical Systems
NasdaqNM:AMMD


Cryogen is the developer and provider of a cost-effective cryotherapy device and system to treat excessive uterine bleeding. The company's initial product is designed to reduce or eliminate the symptoms associated with excessive menstrual bleeding and to provide an alternative to hysterectomy. This is accomplished by using cryoablation which freezes and destroys tissue at extremely low temperatures. The customers include gynecologists, surgery centers, and hospitals.

www.americanmedicalsystems.com
 

DataBeam
White Plains, NY
Invested: March 1992
Acquired by IBM
NYSE: IBM

Databeam is a pioneer in PC videoconferening. The company is a provider of real-time collaboration and distance learning software and developers platforms. Customers include Fortune 500/Global 2000 companies and educational institutions.

www.ibm.com
 

Digital Microwave
San Jose, CA
Invested: February 1984
Nasdaq: STXN

DMC Stratex Networks (FKA Digtial Microwave) is a pioneer in wireless high capacity transmission technology. The company provides cellular network and broadband wireless access solutions that enable, speed and revolutionize the delivery of data, voice and video in global communications. Its customers include service providers in many locations worldwide with varying interconnection and access requirements.

www.dmcstratexnetworks.com
 

DVDPlay
Campbell, CA
Invested: April 2006

DVDPlay is a self-service retail company, initially offering DVD’s for rent from kiosks. The company is transforming the DVD rental business by offering unprecedented convenience, rental costs that are less than one third the industry standard and only the most current titles. DVDPlay’s proprietary retail kiosks offer retailers a new source of revenue as well as a compelling reason for a consumer to visit and return to the store. Total automation and small retail footprint yield excellent business economics.

www.dvdplay.com
 

EndoSonics
Sweden
Invested: October 1984
Acquired by Jomed

EndoSonics is an intraluminal ultrasound technology used for visual imaging in artery functions. Its products enhance the effectiveness of the diagnosis and treatment of cardiovascular disease by aiding cardiologists in identifying diseased arteries, selecting proper treatment, positioning a therapeutic device, treating diseased sites, and assessing results of treatment.

www.jomed.com
 

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EndoTherapeutics
Norwalk, CT
Invested: October 1984
Acquired by U.S. Surgical/Tyco
NYSE: TYC

Endo Therapeutics is a producer of in vivo therapeutic systems and surgical instruments. Included in its product offerings is the disposable trocar for laparoscopy procedures, a port of entry device which allows a telescope to be inserted into the abdomen.

www.ussurg.com
 

EndoVasix
Belmont, CA
Invested: October 1996

Endovasix is a developer of a proprietary technology used to treat acute cerebral arterial clots that cause strokes. Its initial offering is a technology that breaks apart an acute clot in a more effective fashion than thrombolytic drugs, and that can be used adjunctively with a wide array of interventional cardiology and radiology procedures. The target market includes Vascular Neurologists, Interventional Radiologists, NeuroRadiologists, and Cardiologists and Endovascular Surgeons and Neurosurgeons who treat patients who have experienced an occlusive stroke, coronary artery disease, or a peripheral stroke.

 

Eunoe (formerly CS Fluids)
Pleasanton, CA
Invested: October 1998
Acquired by Integra Life Sciences

Eunoe has developed and is testing a pioneering, device-based treatment for Alzheimer's disease. The device is a cerebrospinal fluid shunt that is believed to facilitate the clearance of neurotoxins that may be significant in the progression of Alzheimer's disease. The principal market consists of the 27 million patients worldwide with Alzheimer’s disease.

www.integra-ls.com
 

Fabric7
Mountain View, CA

Invested: July 2004


Founded in May 2002, Fabric7 is delivering a new class of application and service delivery platforms for enterprise datacenters. The company's products are based on an innovative architecture that unifies leading edge ideas in computing, network services, I/O interconnects, virtualization, and datacenter resource management.

www.fabric7.com
 

Gluon Networks
Petaluma, CA

Invested: May 2002
Acquired by Zhone
Nasdaq: ZHNE


Gluon is a developer of converged local switching and management systems for local telecommunications service providers around the world. The company's product is the connecting force linking central offices at the edge of the network with switching and high capacity transmission facilities in the core network using advanced, interworking technology.   Gluon's initial target customers are rural telcos.

www.zhone.com
 

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Hansen Medical
Mountain View, CA
Invested: November 2005
Nasdaq: HNSN

Hansen has developed a robotic catheter control system for precise catheter navigation and control within the chambers of the heart. The first application of the Hansen robotic system will be to enable the RF ablation of atrial fibrillation (AF) arrhythmias in the left atrium. There are 2.2 million US patients suffering from AF with an annual incidence of 160K patients. Drug therapy is inadequate, open surgical procedures have high morbidity rates, and unguided catheter ablation lacks efficacy. Hansen’s robotic technology provides precise guidance and control of the RF ablation catheter thereby enabling more effective and less time consuming AF procedures. Hansen’s robotic system will be applied to other cardiac procedures in the future.

www.hansenmedical.com
 

HemoSense
Milpitas, CA
Invested: November 1997

HemoSense develops portable, handheld analyzers that test the clotting time of whole blood via Prothrombin Time (PT) measurement. These analyzers consist of a low-cost meter and disposable test strips that can be used at home as well as in a physician’s office or clinic setting. They offer a convenient and cost-efficient self-testing solution for patients taking anti-coagulants. The company will target physicians’ offices and anticoagulation clinics.

www.hemosense.com
 

Indigo Medical
Palo Alto, CA
Invested: October 1991
Acquired by Johnson & Johnson
NYSE: JNJ

Indigo Medical is a producer of devices for the urology market. The devices are minimally or non-invasive and allow Benign Prostatic Hyperplasia treatment to take place in a private office setting as opposed to a hospital or an ambulatory surgical center, thereby reducing the costs of treatment.

www.jnj.com
 

Kodiak Technologies
Houston, TX
Invested: June 1999

Kodiak Technologies is a developer and distributor of innovative and technologically advanced shipping containers used in the delivery of temperature sensitive products. The company offers a turnkey solution including a full-service logistics management service and a web-enabled information system that allows for 24x7 ordering, shipment tracking and temperature monitoring. The products are used in commercial, industrial, and medical markets.

www.kodiaktech.com
 

Konarka Technologies
Lowell, MA
Invested: June 2004

Konarka builds products that convert light to energy - anywhere. Konarka is the leading developer of polymer photovoltaic products that provide a source of renewable power in a variety of form factors for commercial, industrial, government and consumer applications. Konarka's photovoltaic technology is focused on delivering lightweight, flexible, scalable and manufacturable products. Konarka has a broad portfolio of patents, technology licenses and an accomplished technical team.

www.konarkatech.com
 

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LightSpeed
Sterling, VA
Invested: March 1996
Acquired by Cisco
Nasdaq:CSCO

Lightspeed is an innovator in voice signaling transmission technology. Its products facilitate interoperability of existing and emerging networks. The target market includes long haul telecommunications carriers whose networks must interface with those of other carriers, particularly those in other countries.

www.cisco.com
 

Luminous Networks
Cupertino, CA
Invested: April 1999
Acquired by Scientific Atlanta and Adtran

Luminous Networks™ is an optical networking company, shipping the industry's first carrier-class optical Ethernet solutions for Metropolitan Area Networks. Its products offer more efficient and cost-effective platforms in solving the last mile bandwidth bottlenecks by dramatically reducing deployment and operational costs. Its primary customers include telecommunications carriers and cable service providers.

www.scientificatlanta.com
www.adtran.com
 

Macromedia
San Francisco, CA
Invested: March 1992

Macromedia is a leader in Internet media technology. The company's products include authoring tools to enable creative and learning professionals to combine text, images, 2D and 3D graphics, animation, sound, and video into a variety of interactive multimedia applications. The Company's customers, from developers to enterprises, use Macromedia solutions to help build compelling and effective Websites and eBusiness applications.

www.adobe.com
 

Mems Optical
Huntsville, AL
Invested: May 2001
Acquired by Jenoptik

MEMS Optical is a leading foundry that manufactures Micro Electrical Mechanical Systems (MEMS) and proprietary “gray scale” micro-optics. The company’s unique confluence of design technologies and manufacturing innovation offers key advantages in the fabrication and distribution of diffractive optics. MemsOptical’s market base is very diverse including leading manufacturers in the fields of fiberoptic communications, storage and biochips.

www.jenoptik.com
 

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Mycogen
Indianapolis, IN
Invested: January 1983
Acquired by Dow Chemical
NYSE: DOW

Mycogen develops biopesticide products using biotechnology and genetic engineering techniques. The company's products are based on microorganisms such as fungi and bacteria which have specific toxic activity against target weeds and insects and are not harmful to closely related plant species or beneficial insects. The company targets chemical and agricultural industries.

www.dowagro.com/mycogen
 

Myelos Corporation
San Diego, CA
Invested: May 1995

Myelos has developed peptide-based therapeutics for nervous system disorders. These small peptides are far more cost-effective to manufacture than full-length recombinant proteins and may be engineered as mimetics to enhance drug efficacy, stability and bioavailability. The target market are physicians treating patients with pain syndromes and a broad range of peripheral neuropathies, including those associated with diabetes, chemotherapy, and nerve injury.

www.myelos.com
 

Network Appliance
Sunnyvale, CA
Invested: September 1993
Nasdaq: NTAP

Network Appliance is a pioneer in network-attached storage. Its software is optimized for file server performance, reliability, and manageability and offers substantially better performance than it's competitors. Customers include technology companies, universities, financial institutions, and government agencies.

www.netapp.com
 

Novalux
Sunnyvale, CA
Invested: May 1998

Novalux has pioneered a breakthrough in ultra-high power lasers for photonic systems called the NECSEL (Novalux Extended Cavity Surface Emitting Laser). This new technology enables elegant, scalable, active laser platforms and solutions for achieving greater information bandwidth across long-haul, metro and local access communications systems. The company's target customers include erbium-doped amplifier manufacturers and transmission systems designers as well as customers in the medical, display, industrial, and lighting markets.

www.novalux.com
 

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Peptimmune
Cambridge, MA
Invested: March 2003

Peptimmune is a biotechnology company which develops specific immunotherapies for the treatment of autoimmune and allergic diseases. The company is using its knowledge of the molecular details of immune cell regulation to create a new generation of potentially safer and more effective drugs for immune disorders.

www.peptimmune.com
 

PhDx
Albuquerque, NM
Invested: June 1994

PhDx is a provider of applications services to healthcare enterprises via the Internet. Its ASP model offers customers demonstrable improvements in patient care by creating efficiencies within an organization, sharing real-time outcomes reports across the continuum of healthcare, measuring the effectiveness of their patient programs or medical products, and data analysis for predictive modeling. Target customers are medical products and pharmaceutical companies, and their customers, which include integrated delivery systems, physician groups, and managed care organizations.

www.phdx.com
 

Phormax
Sunnyvale, CA
Invested: December 2000
Acquired by Alara

Phormax develops high-performance, cost-effective, computed radiography imaging systems. These products enable ease of access to images and improve communications between providers, resulting in improved efficiencies, faster access to diagnoses, fewer lost films, and improved patient care. Target customers include hospitals, outpatient imaging centers, surgery centers, and rehabilitation centers, private physician offices, clinics, and the military.

www.alara.com
 

Polychromix
Woburn, MA
Invested: August 2001

Polychromix develops telecommunications components based on microdevice technology. These products deliver fast, programmable solutions addressing key requirements of dense-wavelength optical networks. Customers are in the optical telecommunications markets.

www.polychromix.com
 

Presto
Mountain View, CA
Invested: November 2006

Presto was founded in 2004 to help families and friends stay connected by making it easier to share digital content. Led by a world-class team of consumer product and technology veterans from AOL, Intuit, Ofoto/Kodak, Palm, Procter & Gamble, TiVo, WebTV/Microsoft and Yahoo!, Presto is redefining digital delivery through a unique service that automatically prints the digital content you want to enjoy, without a computer or Internet connection. Publishing partners for Presto's first product, the Presto Service and HP Printing Mailbox, include Dow Jones & Company, Meredith Corporation and Tribune Media Services. The company, based in Mountain View, Calif., received venture funding from Clearstone Venture Partners, Kleiner Perkins Caufield & Byers and Vanguard Ventures.

www.presto.com
 

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Pyramid Technology
Invested: December 1982
Acquired by Siemens
NYSE: SI

Pyramid Technology Corporation is a pioneer in the Unix minicomputer market. Its products include high-end,